Xiaoguang Fan, PhD, Lecturer of College of Biotechnology, Tianjin University of Science & Technology, Master"s Supervisor.

Main Courses for Undergraduate:

Enzyme Engineering, Professional English of Brewing Technology.

Research interests:
[1] Metabolic analysis and regulation of bacterial microbes.

[2] Screening and application of functional enzymes

Research Projects:
[1] Principal investigator of National Natural Science Fund Project: Effect of compatible solutes glycine betaine supplementation on the metabolic regulation in Escherichia coli (31770037), 2018-2020
[2] Principal investigator of China Postdoctoral Science Foundation: Metabolic engineering of Escherichia coli for the efficient production of cytidine (2018M631747), 2018-2020

[3] Principal investigator of Tianjin High School Science & Technology Fund Planning Project: Reconstruction and regulation of nucleoside synthesis pathway in Escherichia coli by CRISPR/Cas9 technology

Selected Publications:
1. Fan X, Wu H, Jia Z, et al. Metabolic engineering of Bacillus subtilis for the co-production of uridine and acetoin. Applied microbiology and biotechnology, 2018, 102(20): 8753-8762.
2. Fan X, Wu H, Li G, et al. Improvement of uridine production of Bacillus subtilis by atmospheric and room temperature plasma mutagenesis and high-throughput screening. 2017, 12(5): e0176545.
3. Fan X, Cheng G, Zhang H, et al. Effects of acid impregnated steam explosion process on xylose recovery and enzymatic conversion of cellulose in corncob. Carbohydrate polymers, 2014, 114: 21-26.
4. Fan X, Li M, Zhang J, et al. Optimization of SO2 - catalyzed hydrolysis of corncob for xylose and xylitol production. Journal of Chemical Technology and Biotechnology, 2014, 89(11):1720-1726.
5. Zhang H, Fan X, Qiu X, et al. A novel cleaning process for industrial production of xylose in pilot scale from corncob by using screw-steam-explosive extruder. Bioprocess and Biosystems Engineering, 2014: 1-12. (Co-author)
6. Wang L, Fan X, Tang P, et al. Xylitol fermentation using hemicellulose hydrolysate prepared by acid pre-impregnated steam explosion of corncob. Journal of Chemical Technology and Biotechnology, 2013, 88(11): 2067-2074. (Co-author)
7. Zhang C, Qi J, Li Y, Fan X, et al. Production of α-ketobutyrate using engineered Escherichia coli via temperature shift. Biotechnology and Bioengineering, 2016, 113: 2054-2059.
8. Wang S, Li H, Fan X, et al. Metabolic responses in Candida tropicalis to complex inhibitors during xylitol bioconversion, Fungal Genetics & Biology, 2015, 82: 1-8.
9. Wang L, Tang P, Fan X, et al. Effect of selected aldehydes found in the corncob hemicellulose hydrolysate on the growth and xylitol fermentation of Candida tropicalis. Biotechnology Progress, 2013, 29(5): 1181-1189.

10. Wang L, Wu D, Tang P, Fan X, et al. Xylitol production from corncob hydrolysate using polyurethane foam with immobilized Candida tropicalis. Carbohydrate Polymers, 2012, 90(2): 1106-1113.

Contact Information:
Office location: College of Biotechnology, Tianjin University of Science and Technology, No.29, 13th street, Tianjin economic and technological development zone
Postcode: 300457, Tianjin, China
Telephone: 022-60601256
Fax: 022-60602298
Email: xiaoguangfan@tust.edu.cn