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Lectures
PERSONAL INFORMATION
Xia Menglei, Ph.D, Lecturer, College of Biotechnology, Tianjin University of Science and Technology

Research Interests
[1] Process analysis and metabolic regulation of the vital industrial microorganisms
[2] Development of novel technologies for industrial strain breeding and screening
[3] Algorithm and software development for biological process engineering

PUBLICATION
[1] Xia Menglei, Wang Lan, Yang Zhixia, Chen Hongzhang. Periodic-peristole agitation for process enhancement of butanol fermentation. Biotechnology for Biofuels, 2015, 8(1):1-15. 
[2] Xia Menglei, Huang Di, Li Shanshan, Wen Jianping, Jia Xiaoqiang, Chen Yunlin. Enhanced FK506 production in Streptomyces tsukubaensis by rational feeding strategies based on comparative metabolic profiling analysis[J]. Biotechnology and Bioengineering, 2013, 110(10): 2717-2730.  
[3] Xia Menglei, Wang Lan, Yang Zhixia, Chen Hongzhang. High-throughput screening of high Monascus pigment producing strain based on digital image processing and support vector machine . Journal of Industrial Microbiology & Biotechnology, 2015,43(4):451-461.
[4] Xia Menglei, Wang Lan, Yang Zhixia, Chen Hongzhang. A novel digital color analysis method for rapid glucose detection. Analytical Methods, 2015, 7(16):6654-6663. 
[5] Wang Lan, Xia Menglei, Zhang Lianhua, Chen Hongzhang. Promotion of the Clostridium acetobutylicum ATCC 824 growth and acetone–butanol–ethanol fermentation by flavonoids. World Journal of Microbiology and Biotechnology, 2014, 30(7):1969-1976 
[6] Huang Di, Xia Menglei, Li Shanshan, Wen Jianping, Jia Xiaoqiang. Enhancement of FK506 production by engineering secondary pathways of Streptomyces tsukubaensis and exogenous feeding strategies [J]. Journal of Industrial Microbiology & Biotechnology, 2013, 40(9): 1023-1037 
[7] Huang Di, Li Shanshan, Xia Menglei, Wen Jianping. Genome-scale metabolic network guided engineering of Streptomyces tsukubaensis for FK506 production improvement [J]. Microbial Cell Factories, 2013, 12(1): 52.  
[8] Du Wenjie, Huang Di, Xia Menglei, et al. Improved FK506 production by the precursors and product-tolerant mutant of Streptomyces tsukubaensis based on genome shuffling and dynamic fed-batch strategies [J]. Journal of Industrial Microbiology & Biotechnology, 2014, 41(7): 1131-1143. 
[9] Qi Haishan, Li Shanshan, Zhao Sumin, Huang Di, Xia Menglei, Wen Jianping. Model-driven redox pathway manipulation for improved isobutanol production in Bacillus subtilis complemented with experimental validation and metabolic profiling analysis [J]. PloS one, 2014, 9(4): e93815.

College of Biotechnology, Tianjin University of Science and Technology, No. 29, St. No. 13 Tianjin Econmic-Technological Development Area (TEDA), Tianjin 300457, P. R. China 
Tel (mobile): +86 15620931983
Fax: +86 22 60602298
E-mail: mlxia@tust.edu.cn
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