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Professors


Yu Li, Ph. D., Professor, School of bioengineering, Tianjin University of Science and Technology. She is a member of the Chinese Society of Microbiology. She is also a peer reviewer of several SCI journals. At present, she is mainly engaged in the high efficient expression of key enzymes and metabolic regulation of biosynthesis of functional sugar and sugar alcohol, microbial and enzymatic conversion of natural glycosides compounds, and development and application of special protease preparation.


Lecturer course
Undergraduate: 《Microbiology》

Research field 
[1] Biosynthesis of functional sugar and sugar alcohol
[2] Development and application of enzyme preparation 

Grants and Funding
1. The National Key Research and Development Program of China: Preparation of leather enzyme and biotechnology application demonstration, 2017-2021.
2. The National Key Research and Development Program of China: Research on key technologies of green manufacturing of flavoringand ingredients, 2016-2020.
3. National Natural Science Foundation of China: Study on the regulation mechanism of 2 '-fucoidase lactose from Lactococcus lactis, 2019-2022.
4. The National High Technology Research and Development Plan (863): Synthesis of glycol and development of functional glycol, 2012-2015.
5. The National High Technology Research and Development Plan (863): Directional modification of thermally stable low temperature alkaline protease, 2007-2010. 
6. The National Key Research and Development Program of China, Studies on the construction and metabolic regulation of engineering bacteria for the large-scale synthesis of human milk fucosylated oligosaccharide, 2009-2011. 
7. National Science and Technology Basic Condition Platform Project: Standardization and integration of microbial species resources of industrial fermentation, 2005-2008.
8. Tianjin Science and Technology Support project: The scale production of stabilized probiotics and the development of functional additives, 2010-2013. 

Main academic achievements
She has published more than 40 scientific papers, including more than 20 papers indexed by SCI as the first author or corresponding author. She also participated in 15 patents for invention. The main academic papers published are as follows:
[1] Yu Li, Xiaoyan Hu, Jingcheng Sang, Ying Zhang, Huitu Zhang, Fuping Lu*, Fufeng Liu*, An acid-stable β-glucosidase from Aspergillus aculeatus: Gene expression, biochemical characterization and molecular dynamics simulation, International Journal of Biological Macromolecules, 2018: 119 462-469.
[2] Shan Cao,* Ke Wang, Shiting Zhou, Yang Wang, Bing Liu, Baozhen Cheng, and Yu Li*, Mechanism and Effect of High-Basicity Chromium Agent Acting on Cr-Wastewater-Reuse System of Leather Industry, ACS Sustainable Chem. Eng., 2018, 6(3): 3957-3963.
[3] Shan Cao, Qinglong Xin, Shiting Zhou, Bin Xue, Bing Liu, Fuping Lu, Yanping Wang and Yu Li*, B. amyloliquefaciens TCCC 11319, a new Cr(III)-tolerant bacterium for chromium-tanned leather shaving disposal, RSC Advances, 2017, 7: 11455-11461.
[4] Hongbin Wang#, Yu Li#, Yong Zhang, Qinglong Xi, Yueting Cao, Fuping Lu*, Heat acclimation of Bifidobacterium longum and proteomic changes behind it. Probiotics and Antimicrobial Proteins, 2017, 9(3): 255-261.
[5] Shan Cao, Bing Liu, Baozhen Cheng, Fuping Lu, Yanping Wang, Yu Li*, Mechanisms of Zn(II) binded to collagen and its effect on the capacityof ecofriendly Zn-Cr combination tanning system, Journal of Hazardous Materials, 2017, 321: 203-209.
[6] Hui-Min Qin, Songtao Li, Yu-Fu Zhang, Jian-Wen Wang, .Jixuan Li, Shiyi Song, Fuping Lu, Yu Li*, Multienzymatic cascade synthesis of fucosyloligosaccharide via a two-step fermentation strategy in Escherichia coli, Biotechnology Letters, 2016, 38(10): 1747-1752.
[7] Yu Li, Wen-hang Wang, Meng-Cheng Yao, Jiang Li, Xiao-Guang Liu, Fu-Ping Lu*, Fed-batch process development for high cell densitycultivation of Lactobacillus fermentum L1, Journal of Food Agriculture and Environment, 2013, 11(2): 43-47.
[8] Yan Zhang, Yi-han Liu, Yu Li, Xiao-guang Liu, Fu-ping Lu, Extracellular expression of pullulanase from Bacillus naganoensis in Escherichia coli, Annals of Microbiology, 2013, 63(1):289-294.
[9] Yu Li, Gu-Kui Chen, XinWei Tong, Hui-Tu Zhang, Xiao-Guang Liu, Yi-Han Liu, , Fu-Ping Lu*, Construction of Escherichia coli strains producing L-serine from glucose, Biotechnology Letters, 2012, 34(8): 1525-1530.
[10] Honghong Jia, Fuping Lu, Yu Li*, Xiaoguang Liu, Yihan Liu, Hongbin Wang, Jing Li, Yueting Cao, Synthesis of GDP-mannose using coupling fermentation of recombinant Escherichia coli, Biotechnology Letters, 2011, 33(2): 1145-1150.

Contacts: 
Office address: College of Biotechnology, Tianjin University of Science and Technology, No. 29, 13 Street, Tianjin Economic-Technological Development Area (TEDA), Tianjin.
Zip code: 300457
Office phone: 022-60601958
Fax: 022-60602298
Email: liyu@tust.edu.cn

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