GAO Qiang, Ph.D. degree of Eberhard-Karls-Universitaet Tuebingen, Germany; professor of College of Biotechnology of TUST; vice president of avermectin enterprise-college-researcher cooperation union; council member of Tianjin Society of Food Science; visiting scientist of MIT & University of Colorado at Boulder and NREL, USA; member of Chinese and Tianjin Society of Microbiology; New England Branch of Society of Industrial Microbiology, USA.


Undergraduate Courses: Bioengineering English, Frontier Lecture of Biotechnology, Lecture of Food and Biotechnology, Mysterious Microbial World, Introduction to Biotechnology, Introduction to Fermented Food and Ingredients

Graduate Course: Microbial Genetics and Breeding

Education Research

[1] ZHAO Zheng, GAO Qiang, LI Hongjuan, MAO Wenjuan, JIA Yuanyuan, WANG Depei, et al. Chinese Translation of Food Science and Technology (editored by Geoffrey Campbell-Platt), Beijing: China Light Industry Press, 2018, ISBN 9787518415496.

[2] JIA Shiru, GAO Nianfa, BAI Shu, LIU Xiaolan, GAO Qiang (editor). Bioengineering Laboratory Guide (2nd Edn), Beijing: China Light Industry Press, 2010, ISBN 978-7-5019-7751-2.

[3] WANG Depei, YANG Meirong, GAO Qiang. Fostering of Efficient Learning and Innovation Abilities in College Course Study[J]. Education Teaching Forum, 2012, (40):48-49.

Research Interests

[1] Breeding of industrial microorganism and metabolism regulation of fermentation

[2] Metabolic controlled regulation of fermentation

[3] Mechanism of bacterial signal peptide translocation

[4] Microbial metabolomics

Research Projects

[1] China NSFC Program: the mechanism of the twin-arginine translocation signal peptide of food-grad bacterium (31370075). 2014-2017, PI;

[2] National 973 Program: Study on the compatibility of the synthetic microbial systems (2013CB734004). 2015-2017, Sub-PI;

[3] National 863 Program: Key technology of SSF control and development of intelligent equipment (2012AA021302). 2012-2015, Sub-PI;

[4] Key Project for Innovative Research of Tianjin Binhai New Area: Development of thermophilic lignocellulase and its saccharification process (2011-BK-120014). 2011-2013, Co-PI;

[5] Key Project of Tianjin Natural Science Foundation: metabolic engineered strain of Zymomonas mobilis for L-lactate production. 2008-2011, PI;

[6] Honors Project of Tianjin Science and Technology Committee: Breeding of high yield γ-aminobutyrate producer and development of its fermentation process. 2007-2011, PI.

Selected Publications:

[1] Hu D, Ke L, Zhang J, Tan G, Zhang L, Gao Q*. Development and optimization of a fermentation chemically defined medium composition for the production of avermectins by response surface methodology[J]. Chinese Journal of Antibiotics, 2018, 43(8):1055-1061.

[2] Gao Q, Tan G, Xia X, Zhang L*. Learn from microbial intelligence for avermectins overproduction[J]. Current Opinion in Biotechnology, 2017, 48:251-257.

[3] Chang C, Zhang J, Ma S, Wang L, Wang D, Zhang J, Gao Q*. Purification and characterization of glutamate decarboxylase from Enterococcus raffnosus TCCC11660[J]. Journal of Industrial Microbiology & Biotechnology, 2017, 44(6):817-824.

[4] Tian P, Cao P, Hu D, Wang D, Zhang J, Wang L, Zhu Y, Gao Q*. Comparative metabolomics reveals the mechanism of avermectin production enhancement by S-adenosylmethionine[J]. Journal of Industrial Microbiology & Biotechnology, 2017, 44(4-5):595-604.

[5] Shi X, Chang C, MA S, Chen Y, Zhang J, Gao Q*. Efficient bioconversion of L-glutamate to γ-aminobutyric acid by Lactobacillus brevis resting cells[J]. Journal of Industrial Microbiology & Biotechnology, 2017, 44(4-5):697-704.

[6] Cao P, Hu D, Zhang J, Zhang B, Gao Q*. Enhanced avermectin production by rational feeding strategies based on comparative metabolomics[J]. Acta Microbiologica Sinica, 2017, 57(2):281-292.

[7] Gao Q*, Zhao S, Ji Z, Cao P, Hu D. Revealing the novel biosynthesis mechanism of in-ring endoperoxide bond[J]. Scientia Sinica (Vitae), 2016, 46(3):339-340.

[8] Guo G, Tang D, Tian P, Shi X, Cao P, Gao Q*. Optimized sample preparation for metabolome studies on Streptomyces avermitilis by GC-MS[J]. Biotechnology Bulletin, 2015, 31(5):61-67.

[9] Gao Q*, Xv B, Cheng Y, Wang L, Zhang C, Tian P. GFP translocation via twin-arginine secretion pathway in Staphylococcus carnosus[J]. Journal of Tianjin University of Science & Technology, 2014, 29(5):1-5.

[10] Gao Q*, Duan Q, Wang D, Zhang Y, Zheng C. Separation and purification of γ-aminobutyric acid from fermentation broth by flocculation and chromatographic methodologies[J]. Journal of Agricultural and Food Chemistry, 2013, 61:1914-1919.

[11] Gao Q*, Pan C, Liu F, Lu F, Wang D, Zhang J, Zhu Y. Adsorption characteristics of malic acid from aqueous solutions by weakly basic ion-exchange chromatography[J]. Journal of Chromatography A, 2012, 1251:148-153.

[12] Dai XD, Xiang SH, Li J, Gao Q* & Yang KQ*. Development of a colorimetric assay for rapid quantitative measurement of clavulanic acid in microbial samples[J]. Science China (中国科学)-Life Sciences. 201255(2):158-163.

[13] Pan C, Gao Q*, Zheng C, Meng Q, Duan Q, Feng S. Coexpression of two essential isobutanol synthesis genes in Escherichia coli[J]. Microbiology China, 2012, 39(7):912-920.

[14] Gao Q*, Liu F, Zhang T, Zhang J, Jia S, Yu C, Jiang K, Gao N. The role of lactic acid adsorption by ion exchange chromatography[J]. PLoS ONE, 2010, 5(11):e13948.

[15] Müller P, Müller-Anstett MA, Wagener J, Gao Q, Kaesler S, Schaller M, Biedermann T, Götz F*. The Staphylococcus aureus lipoprotein SitC colocalizes with Toll-like receptor 2 (TLR2) in murine keratinocytes and elicits intracellular TLR2 accumulation[J]. Infection and Immunity, 2010, 78(10):4243-4250.

[16] Müller-Anstett MA, Müller P, Albrecht T, Nega M, Wagener J, Gao Q, Kaesler S, Schaller M, Biedermann T, Götz F*. Staphylococcal peptidoglycan colocalizes with Nod2 and TLR2 and activates innate immune response via both receptors in primary murine keratinocytes[J]. PLoS ONE, 2010. 5(10):e13153.


Authorized Chinese Invention Patents:

[1] GAO Qiang, GAO Nianfa, SHI Xiufeng, CHANG Chuanyou, ZHU Yan. A bioconversion method for γ-aminobutyric acid production[P]. ZL 201510626277.X

[2] GAO Qiang, ZHU Yan, MDENG Qingyan, PAN Chaoqiang. A method for a genetically engineered Zymomonas mobilis strain for isopropanol production and its construction[P]. ZL 201210386012.3

[3] GAO Qiang, GAO Nianfa, ZHU Yan, CHEN Huimin, DUAN Qiang, WANG Mengxiao. A method for γ-aminobutyric acid production and its application[P]. ZL 201210003931.8

[4] GAO Nianfa, ZHANG Ying, GAO Qiang, SONG Lei, FENG Yu, ZHANG Jian, WANG Depei. A method forγ-aminobutyric acid overproduction and its application[P]. ZL 201110051732.X

Contact address

Office: College of Biotechnology, Tianjin University of Science & Technology, No. 29, 13th Avenue, TEDA, Tianjin 300457, P.R. China

Postcode: 300457

Office phone: +86-(0)22-60602715

Fax number: +86-(0)22-60602298

Email: gaoqiang@tust.edu.cn