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副教授

李燕军,副教授,硕士生导师,天津市“131”创新型人才工程第三层次人选。2013年毕业于中国科学院过程工程研究所,获工学博士学位。2011年11月至2012年10月中科院公派赴德国弗劳恩霍夫协会学习。利用代谢工程和发酵工程手段开发氨基酸及衍生物的高效生产技术,同时从事谷氨酸棒杆菌的基因编辑技术和系统生物学研究。


主讲课程
微生物学、微生物学实验


承担课题
国家自然科学基金青年科学基金项目,3150010035,谷氨酸棒杆菌MFS木糖转运蛋白研究,2016/01-2019/12,23.8万元,已结题,主持
国家博士后科学基金资助项目,2016M601269,谷氨酸棒杆菌PTS木糖转运途径研究,2016/11-2018/05,5万元,在研,主持
天津市高等学校科技发展基金计划项目,20140603,酶法高效催化合成利巴韦林的研究,2014/09-2017/08,4万元,已结题,主持
广东省发酵与酶工程重点实验室开放项目,谷氨酸棒杆菌色氨酸生物传感系统构建及应用,2018/08-2020/07,4万元,在研,主持
国家863计划项目, SQ2015AA0200416, 有机酸生物合成途径构建与优化技术,159.5万元,已结题,子课题第三完成人
同时主持和参与多项企业横向课题


发表文章
Hongkun Ma, Xiaoguang Fan, ...... Yanjun Li*. Efficient fermentative production of L-theanine by Corynebacterium glutamicum. Applied Microbiology and Biotechnology, 2020, 104:119-130.
Ting Wang, Yanjun Li*, Juan Li, et al. An update of the suicide plasmid-mediated genome editing system in Corynebacterium glutamicum. Microbial Biotechnology, 2019, 12(5):907-919.
Yanjun Li, Dezhi Zhang, Ningyun Cai, et al. Betaine supplementation improved L-threonine fermentation of Escherichia coli THRD by upregulating zwf (glucose-6-phosphate dehydrogenase) expression. Electronic Journal of Biotechnology, 2019, 39:67-73.
Chenglin Zhang#, Yanjun Li#, Jie Ma, et al. High production of 4-hydroxyisoleucine in Corynebacterium glutamicum by multistep metabolic engineering. Metabolic Engineering, 2018, 49:287-298.
Heyun Wu#, Yanjun Li#, Qian Ma, et al. Metabolic engineering of Escherichia coli for high-yield uridine production. Metabolic Engineering, 2018, 49:248-256.
Yanjun Li, Fangqing Yan, Heyun Wu, et al. Multiple‑step chromosomal integration of divided segments from a large DNA fragment via CRISPR/Cas9 in Escherichia coli. Journal of Industrial Microbiology and Biotechnology, 2018, 46(1):81-90.
Yanjun Li, Hongbo Wei, Ting Wang, Qingyang Xu, Chenglin Zhang, Xiaoguang Fan, Ning Chen, Xixian Xie, Current status on metabolic engineering for the production of L-aspartate family amino acids and derivatives. Bioresource Technology, 2017, 245(B):1588-1602
Yanjun Li#, Lanchao Sun#, Jia Feng, Ruifang Wu, Qingyang Xu, Chenglin Zhang C, Ning Chen, Xixian Xie, Efficient production of α-ketoglutarate in the gdh deleted Corynebacterium glutamicum by novel double-phase pH and biotin control strategy. Bioprocess and Biosystems Engineering, 2016, 39(6):967-976
Chenglin Zhang#, Junsheng Qi#, Yanjun Li, Xiaoguang Fan, Qingyang Xu, Ning Chen, Xixian Xie, Production of α-ketobutyrate using engineered Escherichia coli via temperature shift. Biotechnology and Bioengineering, 2016, 113(9):2054-2059
Junpeng Wang, Yan Zhao, Tao Liu, Ting Wang, Chao Han, Qian Mao, Ning Chen*, Yanjun Li*, Effects of heterologous pyruvate carboxylase expression on synthesis of L-threonine in Escherichia coli, International Conference on Applied Biotechnology. Springer, Singapore, 2016, 133-143
Yanjun Li, Uter Merrettig-Bruns*, Sabine Strauch, Stephan Kabasci, Hongzhang Chen, Optimization of ammonia pretreatment of wheat straw for biogas production. Journal of Chemical Technology and Biotechnology, 2015, 90:130-138
Yanjun Li, Xiaowei Peng, Hongzhang Chen*, Comparative characterization of proteins secreted by Neurospora sitophila in solid-state and submerged fermentation. Journal of Bioscience and Bioengineering, 2013, 116(4):493-498
Hongzhang Chen*, Yanjun Li, Fujian Xu, Impact of operating conditions on performance of a novel Gas Double-Dynamic Solid-State Fermentation Bioreactor (GDSFB). Bioprocess and Biosystems Engineering, 2013, 36(11):1753-1758
Hongzhang Chen*, Yanjun Li, Primary Biorefinery of Wheat Straw, In: M.T. Almeida, Wheat: Genetics, Crops and Food Production. 2011, New York: Nova Science Publishers


申请专利
李燕军,徐庆阳,张成林,等. 一种谷氨酸棒杆菌基因编辑方法. 201810446407.5.
李燕军,陈宁,韩洪军,等. iolT1和iolT2蛋白在木糖转运中的应用. 201710149680.7.
谢希贤,李燕军,李娟,等. 过表达异源谷氨酰胺合成酶的基因工程菌及其构建方法. ZL201711031742.0.
李燕军,陈宁,韩洪军,等. 一株谷氨酸棒杆菌及其合成色氨酸的关键基因. ZL201611067957.3.


联系方式
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